Human madness will not end. There will always be extremes and there will always be differences of opinion regarding what is madness and what is sanity. As Jiddu Krishnamurti famously said, it is no measure of health to be well adjusted to such a sick society. But that does not mean we can't improve our situation and that of others by beginning at grass roots levels.
Human "civilization" is at least 5 - 6,000 years old, possibly older, and yet nothing meaningful has changed in our collective and individual psyches. We are evolving technologically and possibily intellectually but not psychologically or emotionally. In many ways we feel more sophisticated, more knowledgable, more capable, but if you look at our situation, inequality is worse than ever in history, our destructive potential is more formidable than ever before, the effects of our presence on Earth more destructive than ever before. When you look at our behavior and its effects, our species acts very much like a cancer - growing without any restraint or sensibility, choking out all competition, destroying our loving host, and putting our very survival at risk. It's nice to imagine that something or someone will come along and change all that but the evidence does not support such a dream. None of our religious, political, or intellectual leaders have made much of a difference overall. Certainly there are regions and groups that do better than others and this fluctuates over time but overall I see little evidence of collective psychological and emotional growth.
While this may sound and feel very discouraging, there is a solution as described above.
We must free ourselves from the shackles of ignorance and limitation imposed by millennia of conditioning and sabotage.
We must discover and remember what it means to be fully human, both individually and collectively.
That can only start by turning inward and looking at the truth of our own personal situation.
For me, this is the core and purpose of spirituality.