There actually are people working in exactly this dimension and wrestling with foundational questions, particularly in relational quantum theory. Carlo Rovelli has written some interesting stuff in this regard. David Bohm as well. Huw Price is another interesting figure who writes on the philosophy of science, particularly regarding time. The entirety of string theory seems rooted in looking for a deeper understanding of what is a particle.
I think that it is so useful and effective to work with the assumption of objective reality that it is difficult to give up. It’s that way with any foundational axioms but theoretical progress requires freedom and creativity, both of which tend to be suppressed by financial and political influences.
Your earlier comment is spot on - we need to take care not to mistake the theory and models for the reality they attempt to represent and explain.