Nature is the 10,000 things including you ! Now we get to the next bit ... what is your true nature ?
I contend that if one is following their khvarenah or 'True Will' they are living in harmony with their true nature and nature itself . If one's True Will is to be an artists but instead you find yourself an unhappy factory worker (or anything else ) then that is against your nature and nature .
Then again we could propose that anything a human does that no other animal does , is against nature .